Influence factors of pressure attenuation method on air tightness test in high-level biosafety laboratory

Presents the main influence factors of pressure attenuation method in air tightness test of the enclosure structure in high-level biosafety laboratories, including atmospheric pressure, room effective capacity, room temperature change and so on . The theoretical calculation and practical test results indicate that in the case of a room with a half-life of 20 min in 500 Pa pressure difference, the leakage rate calculation results are different in different pressure conditions. The leakage rate results vary with the volumes of the process equipment in the room. The determination of qualified room air tightness can not depend on the pressure change range within a period of time when the room temperature changes.